How long does it take to kill all
fleas after first application on an animal
that has fleas?
42 hours to zero fleas counted
24 hours to zero fleas counted
Frontline Plus: 42 hours to zero
fleas counted (24 hours to spread all over
animalís body and 18 hours to kill the
Does it kill ticks as well as fleas?
Yes, but because this product is
licensed as a drug and not as an
insecticide, it can only make label claims
against the species of tick it was tested
for. There is no reason to think other tick
species would not be sensitive. The species
it was tested against is Dermacentor
No, there is no tick activity at all.
This product is highly specific for fleas.
Frontline Plus: Yes, this product
was tested specifically against four tick
species: the deer tick, the lone star tick,
the American dog tick, and the brown dog
Activity against parasites other than
fleas and ticks?
Yes, product is active against ear
mites, sarcoptic mange mites in dogs,
roundworms and hookworms in cats.
Frontline Plus: Fleas and ticks
How long does a single application
Frontline Plus: one month for
ticks, one month for fleas in the cat, 1 to
3 months for fleas in the dog
How soon after bathing can it be applied?
As soon as the pet is dry
As soon as the pet is dry
Frontline Plus: Manufacturer
recommends waiting 2 days after bathing
before applying. The product can be applied
sooner but will take longer to spread over
the body if there is inadequate oil on the
skin as would be the case just after a bath.
Does it wash off?
No - this product is an endectocide,
which means it is absorbed internally and
spreads throughout the body including back
to the skin. Because it acts internally it
cannot be washed off.
Yes - this product will be washed off
completely with a degreasing shampoo. It can
withstand one bath between applications and
swimming once a week between applications
but no more
Frontline Plus: No - this product
remains topical but is stored in the oil
secreting glands of the skin. If the pet
gets wet, the skin layer of product can be
washed off but will be replaced as the oil
producing glands re-secrete it.
Flea killing active ingredient:
Frontline Plus: Fipronil;
Frontline Plus: Fipronil plus Methoprene (methoprene
is a long acting steralizer of fleas)
How young can the pet be for
Puppies - 6 weeks, kittens - 6 weeks
Puppies - 7 weeks, kittens - 8 weeks
Frontline Plus: Puppies -10
weeks, kittens -12 weeks (Frontline Plus
not currently approved for dogs under 11
pounds - approval expected later)
Approved for use in pregnant or
nursing mother dogs/cats?
not in this country but in other
countries yes (U.S. EPA does not recognize
testing done for other countries and testing
in pregnancy/lactation has not been done in
Frontline Plus: no
Does the pet need a veterinarian
office call in the last year to get the
Yes, this is a prescription drug.
No, this is an insecticide, not a drug,
but the manufacturer sells its product for
resale only through veterinarians so that
proper usage etc. can be explained.
Frontline Plus: No, this is an
insecticide, not a drug, but the
manufacturer sells its product for resale
only through veterinarians so that proper
usage etc. can be explained.
Is the product safe for use on sick,
elderly or debilitated patients?
specifically cautions against such use.
Product should be safe for such use
provided the patient is receiving veterinary
care. Otherwise, if the pet is inactive or
hospitalized in a cage, the product may not
spread around the body as rapidly as usual.
Frontline Plus: Product should be
safe for such use provided the patient is
receiving veterinary care otherwise. If the
pet is inactive or hospitalized in a cage,
the product may not spread around the body
as rapidly as usual.
Comes in a 6-pack (3-pack for puppies /
Comes in a 4-pack or a 6-pack.
Frontline Plus: Comes in a 3-pack
or a 6-pack.
Link to manufacturer's web site: